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A 10.5 inch wide wheel takes a 285 to 305 tire and is the rear width on a Corvette, Camaro, Challenger or M4 staggered set. Offset decides where a 22x10.5 ends up. The same wheel tucks at one offset and sits flush at another, and the caliper behind it sets the floor.
352 designs on this site come in 22x10.5, and the same diameter comes in 8 other widths, 22x9, 22x9.5 and 22x10 among them. Most 22x10.5 designs are drilled for 5x112, 5x120 and 5x114.3. Width and offset together set where the tire sits. A 22x10.5 at a high offset tucks, the same wheel at a low offset sits flush or pokes, so pick your car and the page keeps only the 22x10.5 sets that clear, with the aggressive stance option if flush is the goal.